The Anthropocene Campus Philadelphia (ACP) was a collaborative campus event that took place at Drexel University in October 2017 to challenge the familiar boundaries between the environmental studies disciplines, and to open the way for what we believe is a sustainable and provocative research enterprise. This ACP-developed inquiry into Philadelphia and the Delaware Valley engaged with questions of importance to multiple sectors and resonated with other cases in a transnational framework. ACP’s approach included intersecting disciplines, a wide range of actors and experts, and historical time scales from the deep past and into the future. In addition to four primary seminars, the ACP also featured plenary lectures, short workshops, a film series, performances, and a full day set aside for field visits (from historical archives and empty buildings, to brownfield sites and barges) in the region.