The high tide that flooded Venice in November 2019—and the global media coverage of it—served as a stark reminder of the vulnerability of human lives and construction in the face of anthropogenic rising seas. As a city that has danced with a delicate land-water balance since its inception, Venice is emblematic of the ways in which human culture and civilization are directly dependent upon the non-human environments on which they are built. The Anthropocene Campus Venice (ACV) was a one-week forum (October 11–16, 2021) around the theme of Water Politics in the Age of the Anthropocene. It provided a space for co-learning, interdisciplinary collaborations, and comparative studies, bringing together environmental humanities scholars, historians, scientists, geologists, artists, architects, designers, curators and writers. ACV was organized by Ca’ Foscari University of Venice, the Center for the Humanities and Social Change, and the Max Planck Partner Group, The Water City.